Clinical trials and evidence
Clinical trials and real-world evidence support evidence-based medicine in healthcare, playing a pivotal role in validating and advancing medical treatments and interventions. Clinical trials assess the efficacy and safety of new drugs and therapies, with real-world evidence providing data to inform clinical and regulatory decisions based on empirical data.
Top Stories
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News
13 Aug 2024
FDA approves first nasal spray for anaphylaxis
The FDA's approval of neffy offers a needle-free option for treating anaphylaxis, potentially improving patient access and compliance. Continue Reading
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News
30 Jul 2024
New mRNA vaccine initiative targets avian influenza (H5N1)
A new initiative led by WHO and MPP aims to develop mRNA vaccines for avian influenza (H5N1), boosting global pandemic preparedness. Continue Reading
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Feature
01 Feb 2023
Alternatives to Animal Testing Models in Clinical and Biomedical Research
Over the past several years, a growing number of alternative techniques have been developed and used to replace animal testing models in clinical and biomedical research. Continue Reading
By- Alivia Kaylor, MSc
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News
27 Jan 2023
Flexible Prescribing Did Not Increase Buprenorphine Overdose Deaths
A recent study in JAMA Network Open noted that flexible prescribing allowed during the COVID-19 pandemic did not contribute to an increase in buprenorphine overdose-related deaths. Continue Reading
By- Veronica Salib, Assistant Editor
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Feature
24 Jan 2023
The Fundamentals of Animal Testing in Clinical Research
Because humans and animals are biologically similar, animal testing in clinical research helps researchers learn how to prevent, treat, and cure human diseases and ensure product safety. Continue Reading
By- Alivia Kaylor, MSc
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News
23 Jan 2023
HIV Vaccine Study Discontinued at Phase 3 Due to Inadequate Results
According to the HIV Vaccine Trials Network, the Mosaico study, an investigational HIV vaccine study, was discontinued at phase 3 due to inadequate results. Continue Reading
By- Veronica Salib, Assistant Editor
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News
18 Jan 2023
Nutrient Intake Is Inversely Related to Metabolic Syndrome Incidence
A recent study in JAMA Network Open found that intake and serum levels of certain nutrients, namely, folate, vitamin B6, and vitamin B12, are inversely associated with metabolic syndrome incidence. Continue Reading
By- Veronica Salib, Assistant Editor
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Feature
04 Jan 2023
Considerations in Pediatric Clinical Trials, Ensuring Patient Safety
Pediatric clinical trials have the potential to address many unmet needs and gaps in healthcare; however, contemplating the many considerations in pediatric clinical trials is essential for mitigating concerns and ensuring patient safety. Continue Reading
By- Veronica Salib, Assistant Editor
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News
03 Jan 2023
Naloxone Vending Machines Prevented Almost 1,000 Deaths
In a study conducted by the University of Cincinnati in collaboration with Caracole, researchers found that naloxone vending machines prevented nearly 1,000 deaths. Continue Reading
By- Veronica Salib, Assistant Editor
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News
22 Dec 2022
Merck and Moderna Find Success with Cancer Vaccine Clinical Trial
An investigational cancer vaccine using Merck’s Keytruda therapy and Moderna’s mRNA technology proved efficacious in a recent stage 2 clinical trial. Continue Reading
By- Hayden Schmidt
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Feature
14 Dec 2022
Initiating Dementia Treatment, Pharmacological Interventions
Initiating the pharmacological treatment and symptom management of dementia is complex as each of the 55 million people with dementia worldwide has different reactions to currently available medications. Continue Reading
By- Veronica Salib, Assistant Editor
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Feature
13 Dec 2022
Achieving Adequate Pain Management, Pharmacological Indications
Achieving adequate pain management for the 20.4% of adults in the US struggling with chronic pain involves understanding pharmacological indications and contraindications. Continue Reading
By- Veronica Salib, Assistant Editor
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News
12 Dec 2022
AHA Funds Research Network to Advance Clinical Trial Diversity
The AHA announced that it would allocate $4 million to fund its research network to advance clinical trial diversity and equity. Continue Reading
By- Veronica Salib, Assistant Editor
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News
07 Dec 2022
Oral Butyrate Supplementation Treats Pediatric Obesity
In a recent study published by JAMA Network Open, researchers found that oral butyrate supplementation can help treat pediatric obesity, increasing the chance of BMI reduction by 40%. Continue Reading
By- Veronica Salib, Assistant Editor
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News
05 Dec 2022
Comparing Buprenorphine and Methadone for OUD During Pregnancy
In a study published in the New England Journal of Medicine, researchers compared buprenorphine and methadone for OUD during pregnancy, finding that buprenorphine was associated with a lower risk of adverse neonatal events. Continue Reading
By- Veronica Salib, Assistant Editor
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News
01 Dec 2022
FDA Approves $3.5 Million per Dose Hemophilia B Gene Therapy
CSL Behring received FDA approval for Hemgenix, a one-time gene therapy that treats adults with hemophilia B and comes with a considerable price tag. Continue Reading
By- Hayden Schmidt
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Answer
28 Nov 2022
Improving Clinical Trial Diversity Through Community and Pharmaceutical Relationships
Persistent gaps in clinical trial diversity may be improved by building relationships between community sites and pharmaceutical companies through global platforms. Continue Reading
By- Veronica Salib, Assistant Editor
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News
23 Nov 2022
Wound Infiltration May Reduce Pain Following Cesarean Delivery
In a recent publication in JAMA Network Open, researchers found that wound infiltration with local anesthetics during cesarean delivery may reduce postoperative pain and the need for opioids. Continue Reading
By- Veronica Salib, Assistant Editor
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News
22 Nov 2022
FDA Clears Clinical Trials on Investigational New Drug for ALS
On November 15, 2022, NeuroSense announced that the FDA has cleared its investigational new drug (IND), PrimeC, an ALS treatment, for Phase IIb clinical trials. Continue Reading
By- Veronica Salib, Assistant Editor
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News
16 Nov 2022
A Single Dose of Psilocybin Can Reduce MADRS Score
In a study published in the New England Journal of Medicine, researchers found that a high single dose of psilocybin, while associated with adverse events, can reduce the MADRS score in patients with treatment-resistant depression. Continue Reading
By- Veronica Salib, Assistant Editor
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News
15 Nov 2022
Study Finds Increased Prevalence of Nonpharmacological Pain Treatment
A recent study analyzing and comparing pharmacological and nonpharmacological pain management trends between 2011 and 2019 found an increased prevalence of nonpharmacological pain treatment. Continue Reading
By- Veronica Salib, Assistant Editor
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Answer
15 Nov 2022
Exploring Psychedelics to Treat Mental Health Issues
In recent years, many healthcare professionals have highlighted and explored the benefits of psychedelics, such as ketamine, to treat mental health issues including treatment-resistant depression. Continue Reading
By- Veronica Salib, Assistant Editor
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News
14 Nov 2022
How Mesenchymal Stem Cells May Reduce the Need for Antirejection Drugs
A recent press release announced funding for a clinical trial to investigate how mesenchymal stem cells may reduce the need for antirejection drugs following a kidney transplant. Continue Reading
By- Veronica Salib, Assistant Editor
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News
09 Nov 2022
First Humans Transfused with Lab-Grown Blood
The first humans were transfused with lab-grown red blood cells as part of the RESTORE randomized controlled clinical trial. Continue Reading
By- Veronica Salib, Assistant Editor
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News
07 Nov 2022
FDA Approves Investigational Drug Application for Bi-Functional Fusion Protein
The FDA recently approved an investigational new drug application for SIM0237, an anti-PD-L1/IL-15 bi-functional fusion protein. Continue Reading
By- Veronica Salib, Assistant Editor
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News
04 Nov 2022
Valisure Petitions FDA to Recall Dry Shampoos
Valisure petitioned the FDA for recalls on dry shampoos after research in an independent lab found that nearly 70% of samples tested had concerning levels of a cancer-causing chemical, benzene. Continue Reading
By- Veronica Salib, Assistant Editor
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News
03 Nov 2022
RSV Cases Flood Children’s Hospitals as Pfizer Announces Promising Vaccine
Pfizer released positive clinical trial results for its new RSV vaccine as the virus surges across the United States. Continue Reading
By- Hayden Schmidt
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News
01 Nov 2022
Motivational Interventions May Improve SUD Recovery
A randomized clinical trial in JAMA Network Open found that motivational interventions in emergency room settings may improve outcomes and recovery for substance use disorders (SUD). Continue Reading
By- Veronica Salib, Assistant Editor
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Answer
01 Nov 2022
Understanding the Complexities Associated with IgA Nephropathy
In an interview with Jonathan Barrett, PhD, PharmaNewsIntelligence gained an understanding of the complexities associated with IgA Nephropathy, a silent killer, and newly available treatment methods. Continue Reading
By- Veronica Salib, Assistant Editor
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News
31 Oct 2022
Nearly 13% of Oral Anticancer Prescriptions Are Not Received
In a recent article published in JAMA, researchers found that nearly 13% of oral anticancer prescriptions written between January 1, 2018, and December 31, 2019, were not received by patients who needed them. Continue Reading
By- Veronica Salib, Assistant Editor
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News
28 Oct 2022
US Department of Defense Grants $2.97 Million to Treventis
In a recent press release, Treventis announced that the US Department of Defense granted it $2.79 million to develop an anti-tau misfolding drug. Continue Reading
By- Veronica Salib, Assistant Editor
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News
24 Oct 2022
Etripamil Phase III Clinical Trials Are Successful
So far, the Phase III clinical trials for etripamil, a nasal beta blocker, to treat paroxysmal supraventricular tachycardia have been successful. Continue Reading
By- Veronica Salib, Assistant Editor
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News
18 Oct 2022
Orexo Pharmaceuticals Announces Phase I Clinical Study Data
On October 11, 2022, Orexo Pharmaceuticals announced positive phase I clinical study data for OX640, nasal epinephrine. Continue Reading
By- Veronica Salib, Assistant Editor
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News
17 Oct 2022
Diversifying Clinical Trials through Telehealth Platforms
The National Institute of Aging is working to diversify clinical trial registration using a telehealth platform. Continue Reading
By- Veronica Salib, Assistant Editor
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News
14 Oct 2022
How Excluding Disabled Populations from Clinical Trials Impacts Care
In a research article by Health Affairs, clinicians discussed the unjustifiable exclusion of disabled populations from clinician trials and the impacts on care. Continue Reading
By- Veronica Salib, Assistant Editor
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News
13 Oct 2022
J&J Ulcerative Colitis Clinical Trial Produces High Rate of Remission
A Phase 2 clinical trial found that nearly 50% of patients suffering from ulcerative colitis reached clinical remission with a combination of guselkumab and golimumab. Continue Reading
By- Hayden Schmidt
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News
11 Oct 2022
Walmart Launches Clinical Research Mission
In a press statement released today, Walmart launched its clinical research mission focused on marginalized communities. Continue Reading
By- Veronica Salib, Assistant Editor
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News
07 Oct 2022
COVID-19 Vaccination Alters Menstrual Cycle Length
In a global retrospective cohort study, researchers found that COVID-19 vaccination alters menstrual cycle length. Continue Reading
By- Veronica Salib, Assistant Editor
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News
04 Oct 2022
FDA Approves Drug for Open-Angle Glaucoma and Ocular Hypertension
On September 26, 2022, the FDA approved a new drug — in the form of eyedrops — by Santen to treat open-angle glaucoma and ocular hypertension. Continue Reading
By- Veronica Salib, Assistant Editor
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News
30 Sep 2022
Fish Oil Supplements Associated with Risk of Atrial Fibrillation
A recent publication in the European Journal of Preventative Cardiology found that habitual use of fish oil supplements is associated with an increased risk of atrial fibrillation. Continue Reading
By- Veronica Salib, Assistant Editor
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News
21 Sep 2022
How a New Antiviral Therapy May Prevent COVID-19 Transmission
Researchers at the Gladstone Institutes have developed an intranasal antiviral therapy that may prevent COVID-19 transmission. Continue Reading
By- Veronica Salib, Assistant Editor
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News
19 Sep 2022
Pregnant and Lactating Individuals Tolerate COVID Vaccine Boosters
A recent analysis published in JAMA Network Open found that pregnant and lactating individuals tolerate COVID vaccine boosters and third vaccine doses well. Continue Reading
By- Veronica Salib, Assistant Editor
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News
16 Sep 2022
FDA and NIH Launch Partnership for Rare Neurodegenerative Diseases
On September 14, 2022, the FDA announced that it was launching a partnership with the NIH for rare neurodegenerative diseases called the Critical Path for Rare Neurodegenerative Diseases (CP-RND). Continue Reading
By- Veronica Salib, Assistant Editor
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News
15 Sep 2022
Amgen’s Immunotherapy for Lung Cancer Reduces Disease Progression by 34%
Sotorasib, sold under the brand name Lumakras, improved progression-free survival by 34% compared to chemotherapy in patients with KRAS G12C-mutated non-small cell lung cancer (NSCLC). Continue Reading
By- Hayden Schmidt
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News
15 Sep 2022
Biden Administration Appoints Renee Wegrzyn as Director of the ARPA-H
On September 12, 2022, the Biden Administration appointed Renee Wegrzyn, current vice president of business at Ginkgo Bioworks, director of the ARPA-H. Continue Reading
By- Veronica Salib, Assistant Editor
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Answer
14 Sep 2022
Biosimilars Have Saved $12.6 Billion in the US between 2014 and 2022
A recent survey published by Vizient analyzed the adoptability of biosimilars and highlighted the benefits, including $12.6 billion saved between 2014 and 2022. Continue Reading
By- Veronica Salib, Assistant Editor
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News
14 Sep 2022
Democratizing Access to Clinical Trials through Remote Patient Monitoring
Telehealth technologies such as remote patient monitoring and wearable devices hold the key to democratizing access to clinical trials. Continue Reading
By- Glooko
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News
13 Sep 2022
Psilocybin-Assisted Psychotherapy Reduces Heavy Drinking
A recent publication in JAMA Psychiatry found that psilocybin-assisted psychotherapy reduces the number of heavy drinking days in patients with alcohol use disorder. Continue Reading
By- Veronica Salib, Assistant Editor
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News
12 Sep 2022
Glucocorticoids Alter Brain Volume and White Matter Microstructure
A recent study published in BMJ Open found that systemic and inhaled use of glucocorticoids altered brain volume and reduced white matter microstructure integrity. Continue Reading
By- Veronica Salib, Assistant Editor
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News
08 Sep 2022
Paxlovid Advantageous for Elderly COVID-19 Patients, Ineffective in Younger Adults
An Israeli study found that patients over 65 years of age treated with Paxlovid, Pfizer’s protease inhibitor, were significantly less likely to be hospitalized or die due to COVID-19 infection. Continue Reading
By- Hayden Schmidt
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News
07 Sep 2022
Stroke Prevention Study to Analyze Benefits of Wearable Devices
A study at the Center for Arrhythmia Research at Northwestern University received a grant to fund plans to analyze the benefits of wearable devices, such as the Apple Watch, in stroke prevention. Continue Reading
By- Veronica Salib, Assistant Editor
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News
29 Aug 2022
Integrating Real-World and Clinical Trial Data to Improve Patient Outcomes
Integrating real-world data from patient monitoring devices and randomized clinical trial data could improve patient care outcomes, boost clinical trial efficiency, and reduce the cost of clinical studies. Continue Reading
By- Glooko
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News
16 Aug 2022
Hormonal Male Birth Control Product Reaches Late-Phase Clinical Trials
A recent spotlight by the National Institute of Child Health and Human Development (NICHD) highlighted the first hormonal male birth control clinical trial to reach late phases. Continue Reading
By- Veronica Salib, Assistant Editor
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News
12 Aug 2022
Fourth COVID Shot Reduced the Risk of Infection by 12.9%
A recent study in JAMA Network Open found that a fourth COVID shot reduced the risk of SARS-CoV-2 infection by 12.9% compared to people who only had a three-dose series. Continue Reading
By- Veronica Salib, Assistant Editor
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News
10 Aug 2022
Antibiotic Overprescription Is Associated with Worse CKD Outcomes
A publication in JAMA Open Network reported that higher dose prescriptions of the antibiotic fluoroquinolone are associated with an increased risk of adverse CKD outcomes. Continue Reading
By- Veronica Salib, Assistant Editor
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Answer
09 Aug 2022
Addressing Racial Inequities in US Cancer Clinical Trials
New research shows that African American and Latin American populations lacked representation in US cancer clinical trials, underscoring an access to care issue. Continue Reading
By- Alivia Kaylor, MSc
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News
08 Aug 2022
COVID-19 Vaccination Reduced the Risk of Reinfection by Approximately 50%
A recent investigation published in JAMA found that the COVID-19 vaccination reduced the risk of SARS-CoV-2 reinfection by 50%. Continue Reading
By- Veronica Salib, Assistant Editor
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News
05 Aug 2022
Fall COVID Vaccine Boosters Could Prevent over 100,000 Deaths
A recent analysis by the Commonwealth Fund estimates that a fall COVID vaccine booster campaign could prevent over 100,000 deaths. Continue Reading
By- Veronica Salib, Assistant Editor
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News
01 Aug 2022
Astellas and Seagen Announce Results on a Drug for Urothelial Cancer
On July 26, 2022, Astellas and Seagen announced results for a combined drug regimen to treat urothelial cancer in patients unable to receive cisplatin-based chemotherapy. Continue Reading
By- Veronica Salib, Assistant Editor
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News
29 Jul 2022
Paxlovid Reduces Patient Hospitalization Risk by 5 Times
A recent study released by Epic Research found that COVID-19 patient hospitalization risk decreased by five times when taking Paxlovid. Continue Reading
By- Veronica Salib, Assistant Editor
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News
28 Jul 2022
Decreased COVID-19 Vaccination Rates: A Pediatric Health Risk
A recent article from the Kaiser Family Foundation found that pediatric COVID-19 vaccination rates have decreased, which may have implications for health risks. Continue Reading
By- Veronica Salib, Assistant Editor
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News
27 Jul 2022
Increased Rates of Non-Opioid Prescription Following CDC Guidelines
A JAMA publication earlier this year found an increased percentage of non-opioid pain medication prescriptions following the 2016 CDC guidelines. Continue Reading
By- Veronica Salib, Assistant Editor
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News
26 Jul 2022
Global Vaccination Coverage Dropped 5% in 2021
A recent statement from the WHO on immunization coverage found that vaccination rates dropped 5% in 2021. Continue Reading
By- Veronica Salib, Assistant Editor
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News
25 Jul 2022
FDA Grants Abbott Permission to Investigate DBS in Managing Depression
In a July 12 press release, Abbott announced that the FDA granted the company a Breakthrough Device Designation to investigate the use of DBS in managing depression. Continue Reading
By- Veronica Salib, Assistant Editor
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News
22 Jul 2022
Aid Access Discusses Making Abortion Pill Available as Contraception
In a recent interview, Rebecca Gomperts, MD, founder of Aid Access, highlighted plans to make abortion pills available as a weekly contraceptive. Continue Reading
By- Veronica Salib, Assistant Editor
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News
19 Jul 2022
Verve Doses First Patient with Investigational Gene-Editing Medicine
On July 12, 2022, Verve Therapeutics announced the start of phase 1b clinical trials in which they dosed the first human with an investigational in vivo base gene-editing medicine. Continue Reading
By- Veronica Salib, Assistant Editor
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News
18 Jul 2022
Orexo Pharmaceuticals Announces Nasal Adrenaline Clinical Development
A recent press release from Orexo Pharmaceuticals announced their plans to begin clinical development on a nasal adrenaline rescue medication. Continue Reading
By- Veronica Salib, Assistant Editor
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News
15 Jul 2022
Decentralization Tools May Improve Cancer Clinical Trial Enrollment
A recent investigation concluded that decentralizing clinical trials using remote technology and additional tools may help improve cancer clinical trial enrollment. Continue Reading
By- Veronica Salib, Assistant Editor
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News
13 Jul 2022
Psychotropic Medications Linked to an Increased Risk of Parkinson’s
A recent study found that some psychotropic medications may be linked to an increased Parkinson’s disease risk. Continue Reading
By- Veronica Salib, Assistant Editor
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News
11 Jul 2022
Decibel Therapeutics Announces Results of DB-020 Clinical Trial
Decibel Therapeutics announced positive results from early DB-020 clinical trial phases in cancer patients treated with cisplatin. Continue Reading
By- Veronica Salib, Assistant Editor
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News
06 Jul 2022
FDA Approves New Treatment for Large B-Cell Lymphoma
On June 24, the FDA approved a new large B-cell lymphoma treatment as a second line of defense for patients. Continue Reading
By- Veronica Salib, Assistant Editor
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News
05 Jul 2022
FDA Approves New Weight Management Drug for Kids over 12
The FDA recently approved Qsymia, a chronic weight management drug, for pediatric patients over 12. Continue Reading
By- Veronica Salib, Assistant Editor
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News
01 Jul 2022
HPV Vaccine Rates Increase among Adolescents
According to a recent American Academy of Pediatrics publication, human papillomavirus (HPV) vaccine rates have increased among adolescents. Continue Reading
By- Veronica Salib, Assistant Editor
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News
30 Jun 2022
Radiologists Look for Ways to Conserve amidst the Dye Shortage
With the current dye shortage that began in April 2022, a JAMA letter was published discussing ways radiologists can conserve. Continue Reading
By- Veronica Salib, Assistant Editor
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News
29 Jun 2022
Women Are Underrepresented in Clinical Trials, Leading to Health Inequity
A recent study published in Contemporary Clinical Trials found that women were underrepresented in clinical trials, which may be contributing to health inequity. Continue Reading
By- Veronica Salib, Assistant Editor
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News
23 Jun 2022
Vagus Nerve Stimulation Augments Behaviors in Epilepsy Patients
Vagus Nerve Stimulation Augments Behaviors in Epilepsy Patients Continue Reading
By- Veronica Salib, Assistant Editor
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News
22 Jun 2022
FDA Approved Weight-Management Treatment for Bardet–Biedl Syndrome
Late last week, the FDA approved a weight-management treatment for patients with Bardet–Biedl Syndrome. Continue Reading
By- Veronica Salib, Assistant Editor
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News
10 Jun 2022
CDC Report Links People Seeking Substance Misuse Treatment to Psychiatric Issues
A 2019 CDC study links people seeking treatment for substance misuse to moderate-to-severe psychiatric issues across multiple biopsychosocial domains. Continue Reading
By- Alivia Kaylor, MSc
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News
09 Jun 2022
FDA Recommends Emergency Use for Novavax Coronavirus Vaccine
An FDA advisory committee voted unanimously to recommend emergency use authorization for the protein-based Novavax coronavirus vaccine. Continue Reading
By- Hayden Schmidt
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News
08 Jun 2022
Researchers Discover Promising Compound That Kills Hard-to-Treat Cancer Cells
Researchers from the University of Texas Health Science Center have discovered a promising compound that kills hard-to-treat cancer cells in culture and animal models. Continue Reading
By- Alivia Kaylor, MSc
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News
07 Jun 2022
Pfizer-BioNTech’s Expanding Coronavirus Vaccine FDA Approval
Initially marketed as Comirnaty, Pfizer and BioNTech’s coronavirus vaccine has slowly expanded its reach and is eyeing a final stage of FDA approval in the coming months. Continue Reading
By- Hayden Schmidt
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News
03 Jun 2022
Study Finds Vaccination During Pregnancy Decreases Baby’s COVID-19 Risk
A CDC study finds that vaccination during pregnancy decreases the risk of COVID-19 in infants for the first 6 months of life. Continue Reading
By- Alivia Kaylor, MSc
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News
02 Jun 2022
Novartis Gains FDA Approval for Follicular Lymphoma Cell Therapy
FDA issued accelerated approval for Kymriah after the drug achieved an 86% response rate in phase II clinical trials. Continue Reading
By- Hayden Schmidt
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News
01 Jun 2022
Academia Partners with Pharma to Discover New SARS-CoV-2 Drug Treatments
Academia and pharmaceutical experts have partnered to form a regional drug accelerator to develop novel antiviral treatments to combat SARS-CoV-2 and other viruses. Continue Reading
By- Alivia Kaylor, MSc
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News
31 May 2022
Coronavirus Rebound After Pfizer’s Paxlovid Oral Antiviral Drug
The Centers for Disease Control and Prevention (CDC) issued a health advisory to warn providers of the potential for coronavirus recurrence after Paxlovid use. Continue Reading
By- Hayden Schmidt
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News
26 May 2022
FDA Approves First Drug for Chronic Disease Eosinophilic Esophagitis
Monoclonal antibody Dupixent was approved after a successful double-blind clinical trial. Continue Reading
By- Hayden Schmidt
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News
19 May 2022
FDA Lifts Clinical Hold on Gilead’s HIV Treatment, Lenacapavir
FDA based its decision following a review of Gilead’s data on the storage and compatibility of HIV treatment lenacapavir injection with an alternative vial made from aluminosilicate glass. Continue Reading
By- Samantha McGrail
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News
18 May 2022
Bristol Myers Squibb’s Drug Effective in Plaque Psoriasis Patients
The two-year results from the POETYK PSO long-term extension trial showed that plaque psoriasis patients maintained clinical efficacy with deucravacitinib. Continue Reading
By- Samantha McGrail
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News
16 May 2022
Novo Nordisk, Flagship to Develop Rare Disease Treatments
The collaboration will provide access to innovation and leverage the technology platforms of multiple biotech companies to create a portfolio of medicines for rare diseases. Continue Reading
By- Samantha McGrail
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News
12 May 2022
Real-World Evidence Shows Pfizer’s Ibrance Improves Breast Cancer
Real-world evidence shows that Ibrance combined with an aromatase inhibitor (AI) improved overall survival in post-menopausal women and in men with HR+ HER2– metastatic breast cancer. Continue Reading
By- Samantha McGrail
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News
11 May 2022
Bristol Myers Ends Clinical Program for Combination Drug Therapy
All ongoing studies of the combination drug therapy, bempegaldesleukin and Opdivo, will be discontinued based on a pre-planned analysis of two late-stage clinical trials. Continue Reading
By- Samantha McGrail
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News
10 May 2022
Novartis' Antibody Boosts Survival for Squamous Cell Carcinoma
The Phase 3 study found that the IgG4 anti-PD-1 monoclonal antibody improved progression-free survival, objective response rate, duration of response, and safety. Continue Reading
By- Samantha McGrail
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News
10 May 2022
Gilead, Dragonfly to Advance Immunotherapies in Oncology
Under the terms of the agreement, Dragonfly will grant Gilead an exclusive, worldwide license for the 5T4-targeting investigational immunotherapy program, DF7001, in oncology. Continue Reading
By- Samantha McGrail
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News
09 May 2022
Eli Lilly's Obesity Drug Elicits 22.5% of Weight Loss in Adults
The overall average body weight reductions in the obesity drug group were 15% in the 5 mg group, 19.5% in the 10 mg group, 20.9% in the 15 mg group, and 3.1% in the placebo group. Continue Reading
By- Samantha McGrail
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News
09 May 2022
Roche’s Drug Improves Infants with Type 1 Spinal Muscular Atrophy
The FIREFISH study found that 91% of infants treated with Roche’s Evrysdi were alive after three years of treatment and continued to improve or maintain motor functions. Continue Reading
By- Samantha McGrail
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News
05 May 2022
FDA Approves AstraZeneca’s Drug for Generalized Myasthenia Gravis
Other recent FDA approvals include Bristol Myer Squibb’s drug to treat adults with obstructive hypertrophic cardiomyopathy and Mycovia Pharmaceuticals’ drug for vulvovaginal candidiasis. Continue Reading
By- Samantha McGrail
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News
03 May 2022
FDA Accepts AstraZeneca BLA for Hepatocellular Carcinoma Antibody
FDA based the BLA for the hepatocellular carcinoma antibody on a Phase 3 trial, which found that patients treated experienced a 22% reduction in the risk of death versus sorafenib. Continue Reading
By- Samantha McGrail
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News
03 May 2022
Pfizer Reports Positive Phase 2 Data for Lyme Disease Vaccine
The Lyme disease vaccine candidate elicited a similar safety and tolerability profile in patients aged 5–17-years old as adult participants in previous studies. Continue Reading
By- Samantha McGrail
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News
02 May 2022
Sandoz Launches Generic Drug Combination for Ocular Hypertension
The generic drug combination eyedrop, an AB-related generic equivalent to AbbVie’s COMBIGAN, is immediately available to patients via retail pharmacies. Continue Reading
By- Samantha McGrail
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News
29 Apr 2022
FDA Accepts Application for GSK’s Chronic Kidney Disease Drug
The ASCEND Phase 3 clinical trial program found that GSK’s drug improved or maintained hemoglobin (Hb) within the target level for all chronic kidney disease patients. Continue Reading
By- Samantha McGrail
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Feature
27 Apr 2022
Exploring Antidepressants: Selective Serotonin Reuptake Inhibitors (SSRIs)
Selective serotonin reuptake inhibitors are the most commonly prescribed medications for treating major depressive disorder, anxiety disorders, and other psychological conditions. Continue Reading
By- Alivia Kaylor, MSc
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News
25 Apr 2022
FDA Grants Priority Review for Non-Small Cell Lung Cancer Drug
AstraZeneca and Daiichi Sankyo's non-small cell lung cancer drug, Enhertu, elicited an objective response rate of 54.9% and a partial response rate of 53.8%. Continue Reading
By- Samantha McGrail