New Cell Seeder Optimizes Cell Line Development

During the Bioprocess International Conference, Advanced Instruments debuted the Solentim VIPS PRO. This biotechnology is a high efficiency single cell seeder. Cell seeding is the process in which cells are spread for culture. Optimizing cell seeding can improve workflow for cell-line development. Improved workflow, in turn, leads to more significant opportunities for innovation.

"VIPS PRO is a game-changer for single cell seeding, combining powerful, efficient seeding technology with definitive image-based proof — NOT probability — of monoclonality," said Byron Selman, CEO of Advanced Instruments, in the press release. "At Advanced Instruments, customer feedback is integral to what we do and how we design new products. VIPS PRO builds on our trusted VIPS technology with thoughtful updates that meet the needs of our customers."

This device has multiple functions, including automated single cell seeding, intelligent cell detection, and two-step, image-based double-lock assurance of clonality. This seeding technology uses image-based proof alongside proprietary artificial intelligence to improve workflow.

According to the press release, “a major challenge in CLD is providing absolute proof of clonal line generation that regulatory authorities require. VIPS PRO offers a unique double-lock assurance of clonality, generating the two pieces of image-based evidence required for IND submission.”

Other methods, including limiting dilution, require more time from researchers leading to longer clinical manufacturing time. Other devices also have room for human error as they need more direct human tasks. The data collected can be analyzed and managed with the STUDIUS software platform.

Solentim VIPS PRO measures 19.68 × 18.74 × 15.43 inches and 83.77 pounds. It must be maintained at approximately 50–104 °F with a humidity between 20% and 80%.

Researchers are constantly looking for ways to advance their biotechnology for improved research. The use of this device may provide an advantage and accelerate the long and laborious process of clinical research. The cost of this machine remains unclear as the company’s website only lists an option to request a quote. Researchers considering this technology may opt to read the additional materials available on the website and request a quote to conduct a cost-benefit analysis.