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Thermo Fisher Launches Portfolio to Advance Quantitative Analysis

The new mass spectrometry portfolio will boost quantitative analysis, increase workflow throughput through polarity speeds, and boost sensitivity for key target applications.

Thermo Fisher Scientific recently launched a new mass spectrometry (MS) portfolio to advance quantitative analysis. 

The Thermo Scientific TSQ Plus triple quadrupole MS portfolio increases workflow throughput through data acquisition and polarity switching speeds. And the improved low-mass product ion transmission efficiency boosts sensitivity for key target applications. 

The new portfolio consists of the TSQ Altis Plus, TSQ Quantis Plus, and TSQ Fortis Plus MS. Researchers can leverage these tools across various applications, from targeted quantitation to cutting-edge research, a Thermo Fisher spokesperson explained. 

And intuitive mass calibration routines and method optimization, chromatography, and data processing software solutions improve ease to address future analytical challenges.

August Specht, vice president, research and development, chromatography, and mass spectrometry at Thermo Fisher, stated that laboratories need comprehensive workflows to address revolving requirements. 

Thermo Fisher’s MS portfolio helps both identify new compounds of interest and provide fast responses for tackling health risks. Specifically, lab managers, technology leaders, and principal scientists in pharmaceutical laboratories can benefit from the portfolio’s accelerated throughput and improved sensitivity. 

“The TSQ Altis Plus platform is a step forward toward omics-scale, quantitative MS-based methodology for in-depth investigation of metabolism. The unprecedented acquisition speed of the TSQ Altis Plus allows us to maximize the metabolome coverage and significantly enhances the peak definition, essential for accurate quantification,” Julijana Ivanisevic, professor at the University of Lausanne, said in the announcement. 

“The TSQ Altis Plus mass spectrometer allows for robust quantification of low abundant species, thus complementing the comprehensiveness of measured metabolite signature. This increase in productivity, along with the quantitative aspect, is crucial for metabolic phenotyping of human populations – a prerequisite for the transfer to clinical settings,” Ivanisevic continued. 

Groups that leverage the TSQ Plus triple quadrupole MS portfolio will benefit from an increased system uptime due to enhanced quadrupole mass stability, as well as direct instrument method transfers from the existing Thermo Fisher TSQ MS portfolio to the TSQ Plus MS portfolio. 

This transfer will allow for simplified future transfers. 

Additionally, individuals will benefit from integration with mzCloud database to provide Selective Reaction Monitoring (SRM) transition information with predicted collision energy, a Thermo Fisher spokesperson explained. 

And, finally, integration with liquid-and ion-chromatography systems and software delivers robust quantitative application solutions.

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